AI accounting and bookkeeping for biotech, pharma and medtech companies
Biotech accounting.
Runway you can trust.
Battle-tested on 1,000+ companies' books.
Zeni is an accounting firm too. More than 250 of our own accountants, bookkeepers and controllers use this platform every day to close the books for 1,000+ customers, with more than $20 billion in finances processed.¹
Zeni connects your banks, cards and payroll, and our team manages the AI agents and reviews the work. With other AI accounting tools, keeping the agents working is your job.
R&D by program
Tag spend to a program or study as a project, then see OPEX and net burn for each one.
Research services, accrued
Work from labs and research partners billed after the fact is recorded through accrual schedules you approve.
Lab equipment, scheduled
Equipment above your capitalization threshold becomes a fixed-asset schedule for your sign-off.
Runway for the board
Net burn and runway from closed books, plus a 13-week cash forecast from the AI CFO.
An AI Accountant for the books.
An AI CFO for the answers.
The AI Accountant tracks every research dollar. The AI CFO tells you how long the runway is.
Connect your accounts. Get closed books.
Zeni's AI and finance team handle the work in between. You run the science.
Connect your accounts
Banks, cards and payroll. Your Zeni team handles the setup with you.
R&D tracked by program
The AI Accountant codes lab and research spend and tags it to each program.
Zeni closes the books
Zeni's finance team reviews the AI's work and closes the month.
Runway you can trust
Ask the AI CFO for burn, runway and program spend from closed books.
What is biotech accounting?
Biotech accounting is bookkeeping and financial reporting for life sciences companies developing drugs, diagnostics and medical devices. It usually means tracking R&D spend by program, accruing research and clinical services billed after the work is done, capitalizing lab equipment, and reporting burn and runway to investors through long development timelines.
Every entry comes with its reasoning.
Each AI suggestion arrives with its reasoning and confidence. Accrual and fixed-asset schedules wait for your approval, nothing reverses unless someone approves it, and nothing changes in a closed period.
AI CFO · answers from live booksRunway answers before the board asks.
Zeni's AI CFO answers questions on burn, runway and R&D spend by program from your live books, shows how every number was calculated, and builds a 13-week cash forecast.²
Your month-end close, in one workspace.
Thought process on every AI callCoded, with the reasoning attached.
Every lab supply order, research invoice and contractor bill gets a category, class and vendor, plus the reasoning behind it.
Explore transactions →
Prepaid schedule drafted, waiting on your approvalAccruals waiting for sign-off.
Research services billed after the work, lab equipment and annual contracts get accrual, fixed-asset and prepaid schedules that post only after approval.
Explore month-end close →
Receipt matched to its charge, on the recordReceipts matched.
Missing receipts are flagged and matched automatically when they're forwarded or uploaded.
Explore receipts →
AI CFO explains the spike: up 167% from SeptemberFlux before you ask.
Month-over-month variances by vendor, category and class, with an AI summary of what changed.
Explore month-end close →
Found 3 statement transactions missing from the booksReconciled to the statement.
Bank and card accounts are reconciled to statements, with missing transactions flagged and entries suggested.
Explore reconciliation →
Every close task has an owner, a due date and time trackedClose tasks with owners.
Assign owners, priorities and due dates to every close task, so you see who owns what while the month is open.
Explore month-end close →Run more of your finance work in one place.
Class and project reporting
Report by project, including OPEX, net burn, balance sheet and cash flow by program.
Fractional CFO support
Add fractional CFO support for budgets, board decks and fundraising when you need it.
Explore fractional CFO →
Commenting
Comment on any transaction, @mention a teammate and keep the answer on the record.
Explore commenting →What biotech founders ask. What the AI CFO answers.
Built for research-stage companies.
Your team, plus an AI Accountant and AI CFOBiotech and medtech founders and CEOs
Founders of venture-backed companies who need investor-ready numbers through long development timelines.
- Burn and runway any day of the month
- R&D spend by program
- Board packs from closed books
Finance leads and controllers
Finance leads preparing board packs who want the transactional work done first.
- Accrual and fixed-asset schedules for sign-off
- Close tasks with owners and due dates
- Flux and reconciliations drafted for review
Fund the science. Keep the books right.
See the AI Accountant and AI CFO on a biotech company's books.
Biotech accounting and AI bookkeeping FAQs.
- Zeni internal figures, October 2026.
- AI CFO is in beta and can make mistakes; check anything important against the books.
See how Zeni's AI bookkeeping and accounting software works for other teams like yours.
